Dermofill® Volumatic (1 x 10 mL) | Juvanix Laboratories Paris

Short Description

A high-viscosity, macro-volumizing Hyaluronic Acid dermal filler formulated with 25 mg/mL of monophasic cross-linked HA in an economical 10 mL high-capacity syringe. Engineered for deep dermal, subcutaneous, and supraperiosteal placement, Dermofill® Volumatic provides high lifting capacity ($G’$), stable structural projection, and long-lasting tissue support for deep facial fold effacement, cheek and chin augmentation, mandibular border sculpting, and extensive facial volume reconstruction lasting 12 to 18 months.

Detailed Description

Dermofill® Volumatic 10 mL is an advanced, sterile, non-pyrogenic physiological cross-linked sodium hyaluronate injectable developed by Juvanix Laboratories Paris (France). Specifically engineered for deep soft-tissue volumization and facial structural remodeling, it gives aesthetic practitioners the volume capacity and mechanical lift required to reconstruct extensive age-related facial volume deficits, support skeletal bone resorption, and sculpt defined anatomical contours.

Manufactured with advanced monophasic cross-linking technology, Dermofill Volumatic interlocks high-molecular-weight hyaluronic acid into an ultra-dense, homogeneous 3D hydrogel matrix at an optimal 25 mg/mL concentration. This molecular architecture generates high elasticity ($G’$) and cohesive strength, allowing the gel to withstand dynamic facial compression and mechanical shear from hyperactive facial muscles (including the masseter, zygomaticus, and mentalis complexes) without flattening, spreading, or lateral displacement.

Purified through exhaustive multi-stage dialysis washing, unreacted BDDE cross-linker residues and bacterial endotoxins are reduced to negligible trace levels. The resulting hydrogel delivers high biocompatibility, minimal post-injection tissue edema, and predictable in vivo integration. Presented in a generous 10 mL pre-filled syringe, Dermofill Volumatic provides high cost-efficiency and clinical utility, enabling comprehensive full-face contouring from a single clinical unit.

Treatment Areas & Indications

• Midface Structural Volumization & Malar Contouring:

  • Malar and cheekbone augmentation (Zygomatic arch projection)

  • Correction of severe midface volume collapse and deep submalar hollows

  • Support and redensification of deflated medial and deep buccal fat compartments

• Lower Face Contouring & Profile Harmonization:

  • Chin augmentation, anterior projection, and vertical lengthening (retrognathia / microgenia correction)

  • Mandibular angle sharpening and crisp linear jawline sculpting

  • Pre-jowl sulcus effacement and labiomental groove structural elevation

• Deep Facial Folds & Severe Depressions:

  • Severe nasolabial folds requiring deep structural foundation support

  • Deep marionette lines and oral commissure structural descent

• Facial Remodeling & Tissue Repair:

  • Deep temporal fossa hollow restoration (temple lifting)

  • Correction of atrophic facial indentations and traumatic contour asymmetries

Key Clinical Advantages

• High-Capacity 10 mL Format: Specifically calibrated for large-volume structural procedures, eliminating the inconvenience and cost of opening multiple 1.0 mL syringes while maximizing clinic procedural efficiency.

• Optimal 25 mg/mL HA Concentration: Formulated with a dense hyaluronic acid concentration that yields high lifting capacity ($G’$), creating sharp bone-mimetic projection that holds its vertical height in high-tension planes.

• Monophasic Cohesive Matrix: High internal polymer cohesion anchors deep subcutaneous and supraperiosteal boluses at the target anatomical plane, preventing unwanted lateral migration into adjacent soft tissues.

• Exhaustive Dialysis Purification: Rigorous washing cycles eliminate residual cross-linkers and bacterial proteins, significantly minimizing post-procedure tissue swelling, erythema, and downtime.

• Smooth Cannula & Needle Extrusion: Despite its high structural density, the cohesive hydrogel extrudes evenly through 25G/27G needles or 21G/22G microcannulas, providing smooth delivery and uniform retrograde placement.

• Extended Clinical Longevity: Densely cross-linked HA chains provide strong resistance against endogenous hyaluronidase degradation, sustaining structural volume for 12 to 18 months.

Technical Specifications

Professional Advisory: Dermofill® Volumatic 10 mL is a high-density, large-volume medical injectable intended strictly for certified dermatologists, plastic surgeons, and credentialed aesthetic physicians trained in deep facial anatomy, supraperiosteal bolus delivery, and vascular safety protocols. Injection into the breast parenchyma, glabella, periorbital zone, or superficial papillary dermis is strictly contraindicated.