Nabota® 100 Units | Daewoong Pharmaceutical (PrabotulinumtoxinA)

Short Description

An ultra-pure, premium Botulinum Toxin Type A developed using patented HI-PURE™ technology. Nabota® (PrabotulinumtoxinA) is the first South Korean neuromodulator to achieve US FDA approval, engineered with a true 900 kDa high-molecular-weight complex for exceptional stability, precise localized target action, and consistent dynamic wrinkle relaxation.

Detailed Description

Nabota® by Daewoong Pharmaceutical represents an advanced milestone in biological manufacturing, recognized globally under the nonproprietary name PrabotulinumtoxinA (marketed as Jeuveau® in the US and Nuceiva® in Europe). Manufactured in cGMP-certified facilities, Nabota is purified through a proprietary multi-step process that eliminates inactive impurities and uncomplexed fragments, yielding a purity level exceeding 98%.

With a uniform 900 kDa molecular structure identical to the traditional clinical standard, Nabota acts presynaptically by cleaving SNAP-25 proteins. This selective inhibition of acetylcholine exocytosis produces predictable, smooth decontraction of hyperkinetic facial muscles while preserving adjacent tissue integrity and natural patient expressiveness.

Treatment Areas & Indications

• Upper Facial Aesthetics:

  • Moderate-to-severe glabellar frown lines (corrugator and procerus muscles)

  • Transverse frontal forehead rhytids (frontalis muscle)

  • Lateral periorbital wrinkles (crow’s feet / orbicularis oculi)

• Mid-to-Lower Facial Sculpting:

  • Masseter muscle hypertrophy (jawline slimming, facial contouring, and bruxism)

  • Transverse nasal creases (bunny lines)

  • Gummy smile reduction

  • Depressor Anguli Oris (DAO) softening for mouth-angle lifting

  • Mentalis hyperkinesis (chin dimpling / cobblestone chin)

• Body & Therapeutic Indications:

  • Primary axillary and palmar focal hyperhidrosis

  • Trapezius slimming and shoulder line contouring

Key Clinical Advantages

• Patented HI-PURE™ Purification: Proprietary isolation delivers pure 900 kDa active neurotoxin, minimizing foreign protein load and substantially lowering immunogenicity risk over multiple treatment courses.

• Global Regulatory Pedigree: Supported by extensive Phase III clinical comparative studies and cleared by major global authorities, including the US FDA, Health Canada, MFDS, and the EMA.

• Controlled Field of Effect: The heavy 900 kDa complex maintains reliable localized retention at the injection site, reducing the risk of unwanted distant migration.

• Rapid Clinical Onset: Therapeutic relaxation typically begins within 2 to 3 days, with peak cosmetic results establishing at 7 to 14 days and duration lasting between 4 to 6 months.

Technical Specifications

(South Korea)Reconstitution AgentSterile, unpreserved 0.9% Sodium Chloride InjectionStorage ConditionsStore unopened at 2°C to 8°C or frozen at or below -5°C.
Administer within 24 hours after reconstitutionRegulatory StatusMedical Device / Rx — Strict Professional Use Only

Professional Advisory: Nabota® is an authentic prescription-grade medical injectable intended exclusively for qualified medical practitioners, dermatologists, plastic surgeons, and accredited cosmetic clinics. Not permitted for personal purchase or non-clinical administration.