Demure® Ultra (1 x 10 mL) | South Korea

Short Description

A high-capacity, versatile Hyaluronic Acid dermal and body filler formulated with 20 mg/mL of cross-linked HA in an economical 10 mL pre-filled syringe. Calibrated for deep subcutaneous, supra-fascial, and supraperiosteal placement, Demure® Ultra delivers balanced viscoelastic lift ($G’$), smooth tissue integration, and durable structural retention for multi-zone facial contouring (cheeks, chin, jawline), severe fold effacement, and targeted non-surgical body contouring lasting 12 to 24 months.

Detailed Description

Demure® Ultra 10 mL is an advanced, sterile, non-pyrogenic physiological cross-linked sodium hyaluronate injectable manufactured in South Korea. Engineered as the supple, highly adaptable volumizer of the Demure portfolio, it provides aesthetic practitioners with the volume capacity and rheological flexibility needed to treat diffuse soft-tissue deflation, smooth transition zones, and perform broad-scale facial and body rejuvenation without rigid over-projection.

Synthesized using non-animal bio-fermented hyaluronic acid, Demure Ultra utilizes advanced multi-phase cross-linking technology. This process yields a cohesive, monophasic 3D polymer lattice characterized by balanced elasticity ($G’$) and fluid shear-thinning. When placed in deep anatomical planes, the hydrogel integrates smoothly between host tissue layers, adapting dynamically to muscle motion and soft-tissue flexion without forming palpable nodules, surface ridges, or lateral migration.

Thoroughly purified through exhaustive multi-stage dialysis, unreacted BDDE cross-linker monomers and bacterial endotoxins are reduced to negligible trace levels. The resulting hydrogel promotes tissue biocompatibility, minimal post-procedure edema, and short clinical downtime. Supplied as a pure, lidocaine-free formulation, Demure Ultra gives practitioners total freedom to customize anesthesia protocols (such as regional nerve blocks, local infiltration, or custom lidocaine/saline blending) to the patient and anatomical site. Packaged in a 10 mL high-capacity presentation, it delivers significant cost-efficiency and procedural convenience for large-volume protocols.

Treatment Areas & Indications

• Midface Volumization & Soft-Tissue Restoration:

  • Malar and cheekbone contouring with smooth, natural transitions

  • Correction of severe midface volume collapse and deep submalar triangle hollows

  • Redensification of deflated deep fat compartments and accordion lines

• Lower Face Contouring & Harmonization:

  • Chin augmentation, forward projection, and vertical lengthening

  • Mandibular angle definition and linear jawline border sculpting

  • Pre-jowl sulcus effacement and labiomental groove elevation

• Deep Facial Folds & Severe Depressions:

  • Severe nasolabial folds (deep laugh lines) requiring structural support

  • Deep marionette lines and oral commissure structural descent

  • Deep temporal fossa hollow restoration (temple lifting)

• Non-Surgical Body Contouring & Deficit Correction:

  • Lateral pelvic depression filling (hip dip correction)

  • Non-surgical gluteal enhancement and upper/lateral buttock contouring

  • Dorsal hand rejuvenation and soft-tissue replenishment

  • Correction of post-liposuction contour irregularities and traumatic atrophic indentations

Key Clinical Advantages

• High-Capacity 10 mL Presentation: Designed specifically for large-volume procedures, eliminating the inconvenience of opening multiple 1.0 mL syringes while optimizing procedural time and clinic economics.

• Balanced Viscoelastic Adaptation: Calibrated with a smooth, cohesive rheology that provides substantial volumetric lift while flexing naturally under dynamic skin movement, avoiding an unnatural or rigid appearance.

• Anti-Migration Cohesion: Dense cross-linked molecular entanglement prevents product dispersion, ensuring that deep subcutaneous and periosteal deposits remain anchored at the target plane.

• Exhaustive Dialysis Purity: Multi-stage washing cycles reduce unreacted BDDE and endotoxins to non-detectable levels, minimizing post-treatment swelling, erythema, and immune reactivity.

• Pure Lidocaine-Free Formulation: Allows injectors total clinical flexibility to tailor anesthesia (local infiltration, nerve blocks, or cannula blending) according to the patient’s pain threshold and procedural zone.

• Smooth Cannula Glide: Extrudes evenly through 18G–21G body cannulas or 22G–25G facial cannulas, providing continuous extrusion pressure and uniform retrograde fanning.

• Extended Clinical Longevity: Densely cross-linked HA chains resist endogenous hyaluronidase degradation, sustaining aesthetic results for 12 to 24 months.

Technical Specifications

Professional Advisory: Demure® Ultra 10 mL is a prescription-grade medical injectable intended strictly for certified dermatologists, plastic surgeons, and credentialed aesthetic physicians trained in deep facial anatomy, supraperiosteal bolus delivery, and large-bore cannula body contouring. Injection into the breast parenchyma, glabella, periorbital zone, or superficial papillary dermis is strictly contraindicated.