Refinex® 50 Units / 100 Units | Botulinum Toxin Type A
Short Description
A highly purified, versatile Botulinum Toxin Type A injectable available in dual clinical presentations (50 IU and 100 IU). Refinex® is engineered for targeted dynamic wrinkle reduction, facial reshaping, and localized myomodulation, offering aesthetic practitioners high cost-efficiency, predictable diffusion control, and flexible dosing options to eliminate clinic product waste.
Detailed Description
Refinex® is a vacuum-dried Clostridium botulinum type A neurotoxin complex developed for dynamic rhytid correction and functional aesthetic treatments. Available in both 50U and 100U configurations, it allows injectors to precisely match vial volume to clinical requirements—whether administering localized micro-touch-ups or comprehensive full-face rejuvenation.
Operating at the presynaptic motor nerve terminals, Refinex cleaves the SNAP-25 fusion protein, preventing the exocytosis of the neurotransmitter acetylcholine across the neuromuscular junction. This localized chemical denervation produces controlled muscle relaxation, eliminating skin creasing and smoothing hyperdynamic lines while maintaining natural facial balance and expressive dynamics.
Treatment Areas & Indications
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Upper Facial Dynamics:
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Moderate-to-severe glabellar lines (interbrow frown lines / Corrugator and Procerus)
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Horizontal forehead lines (Frontalis muscle relaxation)
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Lateral canthal rhytids (Crow’s feet / Orbicularis oculi)
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Mid & Lower Facial Contouring:
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Masseter muscle hypertrophy (V-line jawline slimming and reduction of bruxism)
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Transverse nasal creases (Bunny lines)
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Perioral vertical lip rhytids (Smoker’s lines) and gummy smile correction
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Mentalis muscle smoothing (Dimpled / cobblestone chin)
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Platysmal neck cords (Nefertiti lift)
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Dermatological & Functional Applications:
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Primary focal axillary and palmar hyperhidrosis
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Micro-botox / intradermal meso-toxin protocols for pore tightening and sebum reduction
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Key Clinical Advantages
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Flexible 50U & 100U Formats: The 50-unit presentation is ideal for single-zone corrections or post-treatment touch-ups, preventing unnecessary vial reconstitution and product expiration, while the 100-unit vial accommodates full-face sessions and higher-dose masseter sculpting.
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Controlled Molecular Dispersion: Formulated to stay localized within the targeted muscle zone, minimizing inadvertent migration into adjacent motor units and lowering the risk of clinical complications like ptosis.
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Rapid Clinical Onset: Patient-noticeable softening typically emerges within 48 to 72 hours, consolidating to maximum smoothing by 10 to 14 days.
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Dependable Longevity: Maintains cosmetic and neuromuscular relaxation for 4 to 6 months, depending on injection technique, anatomical site, and patient metabolic profile.
Technical Specifications
| Parameter | Specification |
| Active Substance | Clostridium botulinum Toxin Type A Neurotoxin Complex |
| Available Strengths | 50 International Units (IU) / 100 International Units (IU) per vial |
| Physical Appearance | Lyophilized / Vacuum-dried white powder in a sealed glass vial |
| Stabilizing Excipients | Dextran, Sucrose, Gelatin / Albumin |
| Reconstitution Agent | Sterile, preservative-free 0.9% Sodium Chloride (Saline) Injection |
| Storage Instructions | Store unopened at -5°C to -20°C or refrigerated at 2°C to 8°C. Protect from direct light. Once reconstituted, refrigerate at 2°C to 8°C and use within 24 hours |
| Regulatory Category | Prescription Only (Rx) — Strictly for Licensed Medical Practitioners |
Professional Advisory: Refinex® is a medical-grade neuromodulator intended strictly for licensed physicians, dermatologists, plastic surgeons, and credentialed aesthetic practitioners. Not authorized for personal purchase, OTC distribution, or home administration.






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