Celosome Strong with Lidocaine (1 x 1.1 mL) | ExoCoBio
Short Description
A high-viscoelasticity Hyaluronic Acid dermal filler formulated with 24 mg/mL of cross-linked HA, 0.3% lidocaine, and patented HENM (High concentration Equalized cross-linked Network Membrane) technology. Designed for deep dermal and subcutaneous placement, Celosome Strong delivers pronounced lifting capacity ($G’$), cohesive tissue support, and sharp contour definition for deep facial folds, malar enhancement, and chin/jawline sculpting lasting up to 12 to 18 months.
Detailed Description
Celosome Strong is an advanced, sterile, non-pyrogenic physiological cross-linked sodium hyaluronate injectable developed by ExoCoBio (South Korea). Engineered to treat severe facial volume deficits and deep tissue depressions, Celosome Strong is manufactured using proprietary HENM technology. This specialized cross-linking method creates a highly organized, dense 3D polymer membrane that maximizes viscoelastic properties while preventing unreacted cross-linker residues.
Subjected to a multi-stage membrane purification process, Celosome Strong eliminates residual BDDE to virtually non-detectable levels, substantially reducing the risk of post-treatment edema, delayed inflammatory reactions, or foreign-body granulomas. With its balanced high elasticity ($G’$) and strong cohesion, Celosome Strong acts as a structural scaffold beneath the skin—holding crisp projection against muscle shear without lateral spreading or migration.
Treatment Areas & Indications
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Deep Facial Folds & Depressions:
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Severe nasolabial folds (deep lines extending from the nasal ala to the mouth corners)
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Deep marionette lines and profound oral commissure descent
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Severe labiomental groove (crease between the lower lip and chin)
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Midface Volumization & Sculpting:
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Malar and cheekbone augmentation (Zygomatic arch projection)
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Restoration of the submalar triangle and deep fat pad deflation
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Lower Face Contouring & Harmonization:
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Chin augmentation, projection, and elongation (microgenia / retrogenia correction)
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Mandibular angle sharpening and jawline border definition
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Pre-jowl sulcus structural correction
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Non-Surgical Profiling:
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Non-surgical rhinoplasty (dorsal bridge straightening and minor tip elevation)
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Key Clinical Advantages
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Patented HENM Technology: Creates an ultra-dense, equalized cross-linked network that yields high elasticity ($G’$) and viscosity, delivering dependable structural lift in deep anatomical planes.
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Ultra-Low BDDE & High Purity: Undergoes an 8-stage membrane filtration protocol that drives residual BDDE down to undetectable levels, optimizing biocompatibility and patient tolerance.
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Cost & Volume Advantage (1.1 mL Format): Features 1.1 mL of hydrogel per syringe (providing 10% extra volume compared to conventional 1.0 mL industry standards), maximizing clinical utility per box.
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Integrated 0.3% Lidocaine: Infused with lidocaine hydrochloride to desensitize the treatment zone during injection, minimizing patient pain and facilitating steady, controlled placement.
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Stable In Vivo Longevity: Highly resistant to endogenous hyaluronidase and oxidative breakdown, sustaining structural volume for 12 to 18 months.
Technical Specifications
| Parameter | Specification |
| Active Substance | Cross-linked Sodium Hyaluronate + 0.3% Lidocaine Hydrochloride |
| HA Concentration | 24 mg/mL |
| Lidocaine Concentration | 3 mg/mL (0.3% w/v) |
| Cross-Linking Technology | HENM (High concentration Equalized cross-linked Network Membrane) |
| Syringe Volume | 1 x 1.1 mL pre-filled sterile glass syringe |
| Included Needles | 2 x 27G 1/2” (13 mm) ultra-thin wall disposable needles |
| Target Injection Plane | Deep dermis and/or subcutaneous layer |
| Recommended Injection Tools | 27G needle or 25G / 27G blunt-tip microcannula |
| Expected Clinical Duration | 12 to 18 months (dependent on patient metabolism, anatomical depth, and volume) |
| Storage Instructions | Store between 2°C to 25°C (36°F to 77°F); protect from direct sunlight and freezing |
| Manufacturer | ExoCoBio Co., Ltd. |
| (South Korea) | Regulatory Category | Medical Device / CE-marked / Prescription Only (Rx) |
Professional Advisory: Celosome Strong with Lidocaine is a medical-grade injectable device intended strictly for certified dermatologists, plastic surgeons, and credentialed aesthetic physicians trained in deep dermal and subcutaneous volumizing protocols. Not authorized for superficial injection or direct consumer use.






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