Xeomin® 100 Units | Merz Aesthetics (IncobotulinumtoxinA)

Short Description

The uniquely purified “naked” neuromodulator by Merz Aesthetics, Xeomin® (IncobotulinumtoxinA) is formulated without unnecessary complexing proteins. Containing only the pure 150 kDa active neurotoxin core, it eliminates foreign protein clutter to virtually eradicate the risk of neutralizing antibody resistance—delivering precise, reliable dynamic line softening and long-term treatment responsiveness.

Detailed Description

Xeomin® is a state-of-the-art Botulinum Toxin Type A biological manufactured in Germany under proprietary XTRACT Technology™ purification standards. Unlike conventional neurotoxins that bind accessory hemagglutinating and non-hemagglutinating proteins around the active core, Xeomin isolates the pure, uncomplexed 150 kDa neurotoxin molecule.

At the presynaptic nerve terminal, IncobotulinumtoxinA selectively cleaves the SNAP-25 protein, temporarily blocking acetylcholine release at the neuromuscular junction. Because it delivers only the therapeutically active component without unnecessary bacterial protein burden, Xeomin minimizes immunological sensitization, making it the premier choice for both treatment-naive patients and long-term neuromodulator recipients concerned with secondary treatment failure.

Treatment Areas & Indications

• Upper Facial Dynamics:

  • Moderate-to-severe glabellar frown lines (Corrugator supercilii and Procerus)

  • Horizontal forehead creases (Frontalis muscle relaxation)

  • Lateral periorbital rhytids (Crow’s feet / Orbicularis oculi)

• Lower Face Contouring & Myomodulation:

  • Masseter muscle hypertrophy (Jawline thinning and bruxism management)

  • Perioral vertical lip lines (Smoker’s lines)

  • Depressor Anguli Oris (DAO) modulation to lift downturned mouth corners

  • Mentalis hyperactivity (Cobblestone / pebbled chin smoothing)

  • Platysmal bands (Nefertiti neck lift)

• Clinical & Therapeutic Applications:

  • Primary axillary and palmar focal hyperhidrosis

  • Cervical dystonia and adult blepharospasm

Key Clinical Advantages

• Zero Complexing Proteins (Pure Core 150 kDa): Free from extraneous bacterial proteins, eliminating unnecessary antigens that can trigger neutralizing antibodies and long-term clinical resistance.

• Ambient Room Temperature Stability: Thanks to its high purification profile and sucrose stabilization, unopened Xeomin vials do not strictly require refrigeration prior to reconstitution (stable at room temperature up to 25°C), simplifying clinic logistics and transport.

• Equipotent 1:1 Clinical Dosing: Exhibits a direct 1:1 dose equivalence with OnabotulinumtoxinA (Allergan Botox), allowing seamless protocol integration without complex unit recalculations.

• Natural Expressive Outcomes: Provides predictable localized relaxation with minimal lateral dispersion, preserving subtle facial expressions without a “frozen” appearance.

• Dependable Onset & Longevity: Muscle decontraction begins within 3 to 4 days, with full clinical effect visible at 10 to 14 days and sustained performance lasting 3 to 4+ months.

Technical Specifications

Once reconstituted, store refrigerated at 2°C to 8°C and use within 24 hoursRegulatory StatusPrescription Medicine (Rx) — Strictly for Licensed Medical Practitioners

Professional Advisory: Xeomin® is a medical-grade neuromodulator intended strictly for licensed physicians, dermatologists, plastic surgeons, and credentialed aesthetic practitioners. Not intended for direct consumer or home use.