Dermofill® Volumizer (1 x 10 mL)
Short Description
A high-viscosity, macro-volumizing Hyaluronic Acid dermal and body filler formulated with high-density cross-linked HA in an economical 10 mL presentation. Engineered for deep subcutaneous and supraperiosteal placement, Dermofill® Volumizer provides high lifting capacity ($G’$), cohesive structural projection, and long-lasting shape retention for extensive mid-to-lower facial reconstruction, cheek and chin augmentation, mandibular sculpting, and non-surgical body contouring lasting 12 to 18+ months.
Detailed Description
Dermofill® Volumizer 10 mL is an advanced, sterile, non-pyrogenic physiological cross-linked sodium hyaluronate injectable designed for significant soft-tissue augmentation and structural remodeling. Formulated using non-animal bio-fermented hyaluronic acid, it provides practitioners with a high-capacity volumizing solution capable of reconstructing deep anatomical volume collapse, strengthening bone-level projection, and correcting broad tissue deficits without surgical intervention.
Manufactured with advanced multi-stage cross-linking technology, Dermofill Volumizer interlocks HA chains into a dense, high-cohesion 3D polymeric hydrogel matrix. This molecular architecture generates superior elasticity ($G’$) and internal cohesivity, enabling the filler to withstand heavy muscular shear forces (such as the masseter, mentalis, and gluteal muscle complexes) and mechanical gravity without flattening, lateral displacement, or product migration.
Thoroughly washed through extensive dialysis filtration, unreacted residual BDDE and bacterial endotoxins are reduced to non-detectable trace levels, ensuring high tissue biocompatibility, reduced post-procedure edema, and minimal patient downtime. Formulated as a pure lidocaine-free hydrogel, it allows clinicians full flexibility to customize patient-specific anesthesia protocols (such as localized infiltration or cannula blending) according to procedural needs.
Treatment Areas & Indications
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Midface Structural Volumization & Sculpting:
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Malar and cheekbone augmentation (Zygomatic arch projection)
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Correction of severe midface volume collapse and deep submalar hollows
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Support and redensification of deep fat pad deflation
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Lower Face Contouring & Profile Harmonization:
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Pronounced chin augmentation, anterior projection, and vertical lengthening (retrognathia / microgenia correction)
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Mandibular angle sharpening and crisp linear jawline sculpting
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Pre-jowl sulcus structural effacement and marionette line elevation
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Deep Facial Folds & Severe Depressions:
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Severe nasolabial folds requiring deep structural foundation support
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Deep temporal fossa hollow restoration (temple lifting)
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Non-Surgical Body Contouring & Reconstruction:
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Gluteal volume enhancement and lateral hip dip filling
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Correction of post-traumatic or post-surgical atrophic tissue indentations
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Dorsal hand rejuvenation and subcutaneous volume replenishment
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Key Clinical Advantages
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High-Capacity 10 mL Presentation: Specifically packaged for large-volume structural procedures, eliminating the inconvenience and cost of opening multiple 1.0 mL syringes while maximizing clinical ROI.
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High Elastic Modulus ($G’$) & Projection: Generates high resistance to tissue compression and gravity, holding defined vertical height and bone-mimetic architecture in high-tension planes.
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Cohesive Matrix Resistance to Migration: High internal polymer cohesion anchors deep subcutaneous and periosteal deposits at the targeted plane, preventing spreading into adjacent superficial compartments.
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High-Purity Bio-Fermented Matrix: Undergoes rigorous dialysis washing to remove chemical cross-linking residues and endotoxins, significantly reducing the risk of delayed inflammatory granulomas or tissue edema.
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Anesthetic Versatility (Lidocaine-Free): Provides a pure hyaluronic acid formulation that gives injectors total freedom to tailor regional nerve blocks, tumescent anesthesia, or lidocaine admixtures per individual patient requirements.
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Extended Clinical Durability: Densely cross-linked HA chains provide strong resistance against endogenous hyaluronidase degradation, sustaining aesthetic volume for 12 to 18+ months (and up to 24 months in stable body/structural zones).
Technical Specifications
| Parameter | Specification |
| Active Substance | Cross-linked Sodium Hyaluronate (non-animal bio-fermentation) |
| HA Concentration | 20 – 25 mg/mL (High-density macro-volumizing matrix) |
| Cross-Linking Technology | Multi-Stage High-Viscoelastic 3D Polymer Matrix (BDDE-based) |
| Lidocaine Content | Lidocaine-free (Pure HA gel for customized pain management) |
| Packaging Presentation | 1 x 10 mL pre-filled sterile syringe (Total 10.0 mL) |
| Target Injection Plane | Deep subcutaneous tissue, supra-fascial layer, or supraperiosteal plane |
| Recommended Injection Tools | 18G / 21G blunt-tip microcannula (body/hip dips) or 22G / 25G microcannula (facial contouring) |
| Recommended Injection Techniques | Retrograde linear fanning, bolus supraperiosteal layering, or multi-planar subcutaneous tunneling |
| Expected Clinical Duration | 12 to 18+ months (up to 24 months depending on anatomical site and metabolic rate) |
| Storage Instructions | Store between 2°C to 25°C (36°F to 77°F); protect from direct sunlight and freezing |
| Regulatory Category | Medical Device / CE-marked / Prescription Only (Rx) |
Professional Advisory: Dermofill® Volumizer 10 mL is a high-density, large-volume medical injectable intended strictly for certified dermatologists, plastic surgeons, and credentialed aesthetic physicians trained in deep structural placement, large-bore cannula body contouring, and vascular safety protocols. Injection into the breast parenchyma, superficial dermis, or vascular danger zones is strictly contraindicated.






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