Celosome Implant with Lidocaine (1 x 1.1 mL) | ExoCoBio
Short Description
The highest-density structural volumizer in the Celosome portfolio, Celosome Implant with 0.3% Lidocaine is engineered with ExoCoBio’s patented HENM (High concentration Equalized cross-linked Network Membrane) technology. Featuring the highest elastic modulus ($G’$) and viscosity in the range, it is specifically designed for deep subcutaneous and supraperiosteal placement to deliver bone-mimetic projection, sharp mandibular contouring, pronounced chin augmentation, and non-surgical rhinoplasty lasting 12 to 24 months.
Detailed Description
Celosome Implant is a high-density, sterile, non-pyrogenic physiological cross-linked sodium hyaluronate injectable developed by ExoCoBio (South Korea). Positioned as the most structurally robust filler in the Celosome series, it functions as a semi-permanent biological scaffold to reconstruct lost facial architecture and provide profound skeletal-level support.
Manufactured using proprietary HENM technology, Celosome Implant interlocks cross-linked hyaluronic acid into an ultra-dense, equalized multi-layered membrane matrix. This dense molecular packing yields extreme cohesive strength and shear deformation resistance, enabling the gel to withstand intense muscular compression (such as the mentalis and masseter muscles) without flattening, spreading, or lateral displacement. Purified through an exhaustive 8-stage membrane dialysis process, residual BDDE is reduced to non-detectable levels, minimizing post-injection tissue swelling and immune reactivity.
Treatment Areas & Indications
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Lower Face Contouring & Profile Harmonization:
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Chin augmentation, forward projection, and vertical lengthening (correction of retrognathia and microgenia)
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Mandibular angle sharpening and crisp linear jawline sculpting
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Structural effacement of the pre-jowl sulcus
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Midface Bone-Mimetic Volumization:
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Malar and zygomatic arch deep structural projection
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Severe midface volume depletion and submalar deficiency
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Non-Surgical Rhinoplasty:
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Nasal dorsum elevation, bridge straightening, and structural columella support
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Deep Facial Volume Reconstruction:
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Deep temporal fossa reconstruction
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Severe age-related bone resorption and structural fat pad atrophy
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Key Clinical Advantages
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Maximum Elastic Modulus ($G’$) & Projection: Boasts the highest lifting capacity in the Celosome range, delivering sharp, defined structural projection that mimics natural bone structure without softening.
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Superior Resistance to Lateral Migration: The high cohesion of the HENM membrane ensures that deep boluses stay anchored at the target supraperiosteal plane, preventing gel spreading into adjacent soft tissues.
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8-Stage Dialysis Purification: Rigorous membrane filtration virtually eliminates unreacted BDDE monomers and endotoxins, significantly reducing the incidence of delayed-onset inflammation, edema, and granulomatous reactions.
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Cost & Volume Advantage (1.1 mL): Supplied in a 1.1 mL pre-filled syringe—providing 10% more product than conventional 1.0 mL industry alternatives for broader clinical utility.
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Integrated 0.3% Lidocaine: Infused with lidocaine hydrochloride to desensitize deep tissues during needle or cannula extrusion, ensuring high patient comfort during high-resistance bolus delivery.
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Extended Clinical Longevity: Dense cross-linking provides superior resistance to mechanical shear and hyaluronidase degradation, maintaining structural projection for 12 to 24 months.
Technical Specifications
| Parameter | Specification |
| Active Substance | Cross-linked Sodium Hyaluronate + 0.3% Lidocaine Hydrochloride |
| HA Concentration | 24 mg/mL (Maximum structural density) |
| Lidocaine Concentration | 3 mg/mL (0.3% w/v) |
| Cross-Linking Technology | HENM (High concentration Equalized cross-linked Network Membrane) |
| Packaging Presentation | 1 x 1.1 mL pre-filled sterile glass syringe |
| Included Needles | 2 x 25G 1/2” (13 mm) or 27G 1/2” ultra-thin wall disposable needles |
| Target Injection Plane | Supraperiosteal (pre-periosteal) plane or deep subcutaneous layer |
| Recommended Injection Tools | 25G / 27G needle or 22G / 25G blunt-tip microcannula |
| Expected Clinical Duration | 12 to 24 months (dependent on anatomical site, depth, and patient tissue metabolism) |
| Storage Instructions | Store between 2°C to 25°C (36°F to 77°F); protect from direct sunlight and freezing |
| Manufacturer | ExoCoBio Co., Ltd. |
| (South Korea) | Regulatory Category | Medical Device / CE-marked / Prescription Only (Rx) |
Professional Advisory: Celosome Implant with Lidocaine is an authentic high-density medical injectable intended strictly for certified dermatologists, plastic surgeons, maxillofacial surgeons, and qualified aesthetic injectors trained in deep periosteal delivery and vascular anatomy. Not intended for superficial dermal application or non-clinical consumer use.






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