uvéderm® Ultra 3 (2 x 1.0 mL) | Allergan Aesthetics
Short Description
A versatile, cohesive Hyaluronic Acid dermal filler formulated with 0.3% lidocaine and Allergan’s proprietary Hylacross™ technology. Juvéderm® Ultra 3 is specifically calibrated for correcting moderate to severe facial depressions, softening pronounced nasolabial folds and marionette lines, and restoring natural, supple lip volume with exceptional tissue integration.
Detailed Description
Juvéderm® Ultra 3 is an advanced, sterile, physiological cross-linked hyaluronic acid gel of non-animal origin, engineered by Allergan Aesthetics (an AbbVie company). Built upon patented Hylacross™ technology, Ultra 3 features a uniquely monophasic, smooth-consistency gel structure rather than a particulate or granular suspension. This molecular architecture ensures smooth, uniform extrusion forces and seamless intradermal blending.
With a balanced viscosity and high elasticity ($G’$), Juvéderm Ultra 3 provides both structural lift and fluid dynamic flexibility. It integrates directly into the targeted dermal matrix to immediately restore volume, bind local moisture, and mechanically efface deep skin creases while allowing the face to move with complete natural fluidity.
Treatment Areas & Indications
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Mid-to-Deep Facial Folds & Depressions:
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Moderate-to-severe nasolabial folds (smile lines running from the nose to mouth)
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Marionette lines and downturned oral commissures
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Perioral vertical rhytids (moderate smoker’s lines)
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Lip Augmentation & Perioral Sculpting:
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Moderate lip volume enhancement and mucosal plumping
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Definition of the vermilion border and Cupid’s bow contour
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Facial Contouring & Touch-ups:
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Shallow-to-medium cheek crease softening
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Chin crease (labiomental fold) smoothing
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Key Clinical Advantages
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Patented Hylacross™ Technology: Delivers a high concentration of cross-linked HA in a completely homogeneous, non-particulate gel matrix that resists premature in vivo enzymatic breakdown.
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Integrated 0.3% Lidocaine: Formulated with lidocaine hydrochloride to desensitize the treatment zone upon injection, optimizing patient comfort and procedural compliance.
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Natural Dynamic Tissue Integration: The monophasic cohesive matrix conforms smoothly to subcutaneous facial dynamics, preventing palpable lumps, gel displacement, or surface irregularities.
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Sustained Longevity: Highly resistant to free radical and hyaluronidase degradation, offering clinical durability typically lasting up to 12 months post-treatment.
Technical Specifications
| Parameter | Specification |
| Active Substance | Cross-linked Hyaluronic Acid + 0.3% Lidocaine Hydrochloride |
| HA Concentration | 24 mg/mL |
| Lidocaine Concentration | 3 mg/mL (0.3% w/w) |
| Cross-Linking Technology | Hylacross™ (BDDE cross-linked, monophasic cohesive gel) |
| Packaging Presentation | 2 x 1.0 mL pre-filled sterile glass syringes (Total 2.0 mL) |
| Included Needles | 4 x 27G 1/2” ultra-thin wall disposable needles |
| Target Injection Plane | Mid-to-deep dermis and lip mucosal tissue |
| Injection Technique | Linear threading, serial puncture, cross-hatching, or retrograde micro-bolus |
| Expected Duration | Up to 12 months (dependent on anatomical site, depth, and patient metabolism) |
| Storage Specifications | Store at 2°C to 25°C (36°F to 77°F). Protect from freezing and direct sunlight |
| Manufacturer | Allergan Aesthetics / AbbVie (Manufactured in Pringy, France) |
| Regulatory Category | CE-marked Class III Medical Device / Prescription Only (Rx) |
Professional Advisory: Juvéderm® Ultra 3 is a medical-grade injectable device intended exclusively for certified dermatologists, plastic surgeons, and licensed aesthetic injectors. Not intended for home administration or over-the-counter retail distribution.









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