Jalupro® Super Hydro (1 x 2.5 mL) | Professional Derma SA
Short Description
An advanced, deep-tissue biorevitalizing biostimulator formulated with 80 mg of hybrid dual-molecular-weight Hyaluronic Acid (32 mg/mL), a concentrated 7-Amino-Acid cluster, and 3 biomimetic peptides. Calibrated for targeted deep subcutaneous and facial retaining ligament biostimulation, Jalupro® Super Hydro reinforces the structural connective framework, counteracts severe tissue laxity, and delivers a noticeable vector lift and dermal redensification with clinical results lasting 6 to 9 months.
Detailed Description
Jalupro® Super Hydro is a sterile, non-pyrogenic, absorbable physiological injectable solution developed by Professional Derma SA (Switzerland / Italy). Engineered specifically to target age-related fascial laxity, structural volume deflation, and the descent of facial retaining ligaments, it shifts the biostimulation paradigm from superficial epidermal hydration to deep structural connective-tissue remodeling.
The formulation utilizes a three-tier molecular synergy:
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Hybrid Dual-Molecular-Weight Hyaluronic Acid (80 mg total / 32 mg/mL): Unites high-molecular-weight HA (2,000 kDa) and low-molecular-weight HA (200 kDa). The high-molecular-weight chains provide immediate scaffolding support and extracellular matrix hydration, while the low-molecular-weight fragments activate CD44 receptors, stimulating intrinsic hyaluronic acid synthesis and cellular signaling without chemical cross-linking agents (zero BDDE).
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Reinforced 7-Amino-Acid Cluster: Supplies high concentrations of Glycine, L-Proline, L-Lysine HCl, L-Leucine, L-Alanine, L-Valine, and L-Arginine. This specific stoichiometric ratio provides the exact biochemical precursors required by fibroblasts to assemble pro-collagen alpha-chains into stable, triple-helical Type I and Type III collagen bundles, as well as native elastin fibers.
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Biomimetic Peptide Complex (3 Peptides):
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Acetyl Decapeptide-3: Stimulates cellular proliferation and supports extracellular matrix (ECM) repair.
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Oligopeptide-24: Activates cellular turnover and boosts fibroblast transcription of collagen and elastin.
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Acetyl Tetrapeptide-5: Enhances microcirculation, supports lymphatic drainage, and assists in reducing tissue edema and fluid retention.
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When administered into deep subcutaneous layers and retaining ligament anchor zones (such as the zygomatic, platysma-auricular, and mandibular ligaments), Jalupro Super Hydro reinforces the fibrous septa and deep fascial framework, producing a natural mechanical lifting effect and restoring facial contour definition.
Treatment Areas & Indications
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Facial Retaining Ligament Rejuvenation & Vector Lifting:
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Subcutaneous anchor points along the zygomatic retaining ligament
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Upper masseteric and parotid-cutaneous ligament planes
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Platysma-auricular fascia reinforcement
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Mandibular ligament and pre-jowl sulcus structural support
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Severe Cutaneous Laxity & Deep Tissue Deflation:
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Sagging lower face contours and drooping jowl margins
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Flattened malar prominence and descending midface soft tissues
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Pronounced accordion lines and midface skin crepeyness
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Neck & Submental Firming:
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Submental flaccidity and horizontal neck rings (“necklace lines”)
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Platysmal band softening and lateral neck tissue redensification
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Key Clinical Advantages
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High Total HA Load (80 mg / 2.5 mL): Delivers 32 mg/mL of pure, non-cross-linked hybrid HA—one of the highest concentrations available in biorevitalizing injectables—providing deep structural hydration without hydrophilic over-expansion or vascular occlusion risk.
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Direct Ligament Biostimulation (LBD Technique): Designed for deep suprafascial and ligamentous deposition, rejuvenating the facial support scaffolding that holds superficial fat pads and skin in place.
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Zero BDDE / High Safety Profile: Completely free of synthetic chemical cross-linking agents, eliminating risks of delayed foreign-body granulomas, sterile abscesses, or immune rejection.
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Low Downtime 6+1 BAP Injection Protocol: Optimized for standardized deep-bolus micro-injections (6 facial points plus 1 optional chin/mandibular point per side), minimizing needle passes, bruising, and patient discomfort.
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Complete ECM Bio-Nourishment: Combines both cellular signaling peptides and raw amino acid building blocks, sustaining endogenous collagen and elastin synthesis over an extended regenerative window.
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Extended Multi-Month Performance: Deep ligamentous remodeling and newly synthesized collagen matrices maintain firming and lifting benefits for 6 to 9 months following an induction protocol.
Technical Specifications
| Parameter | Specification |
| Product Classification | Deep Tissue Biorevitalizing Biostimulator / Class III Medical Device |
| Hyaluronic Acid Content | 80 mg total per syringe (32 mg/mL) |
| HA Molecular Weights | Hybrid Matrix: High Molecular Weight (2,000 kDa) + Low Molecular Weight (200 kDa) |
| HA Cross-Linking Status | Non-cross-linked linear physiological HA (BDDE-Free) |
| Amino Acid Complex (7 AAs) | Glycine, L-Proline, L-Lysine HCl, L-Leucine, L-Alanine, L-Valine, L-Arginine |
| Biomimetic Peptides (3 Peptides) | Acetyl Decapeptide-3, Oligopeptide-24, Acetyl Tetrapeptide-5 |
| Syringe Presentation | 1 x 2.5 mL pre-filled sterile glass syringe |
| Target Injection Plane | Deep subcutaneous layer, supra-fascial plane, and deep retaining ligament anchor sites |
| Recommended Injection Tools | 27G 1/2” (13 mm) needle or 25G / 27G (38–50 mm) blunt-tip microcannula |
| Recommended Protocol | Induction: 2 sessions spaced 1 month apart; Maintenance: 1 session every 5 to 6 months |
| Standard Delivery Technique | 6+1 BAP (Bio Aesthetic Points) deep bolus technique (0.2 mL per bolus) or retrograde fanning via cannula |
| Expected Clinical Duration | 6 to 9 months |
| Storage Instructions | Store between 2°C to 25°C (36°F to 77°F); protect from direct light and freezing |
| Manufacturer / Origin | Professional Derma SA (Lugano, Switzerland / Italy) |
| Regulatory Category | CE-marked Class III Medical Device (CE 0373) / Prescription Only (Rx) |
Professional Advisory: Jalupro® Super Hydro is an advanced medical device strictly intended for certified dermatologists, plastic surgeons, and credentialed aesthetic physicians trained in deep facial anatomy, facial retaining ligament vectors, and vascular mapping. Intravascular or superficial epidermal injection is strictly contraindicated.






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