Celosome Soft with Lidocaine (1 x 1.1 mL) | ExoCoBio
Short Description
An ultra-fine, low-viscosity Hyaluronic Acid dermal filler formulated with 24 mg/mL of cross-linked HA, 0.3% lidocaine, and patented HENM (High concentration Equalized cross-linked Network Membrane) technology. Specifically calibrated for superficial-to-mid dermal placement, Celosome Soft is engineered to erase superficial fine lines, delicate perioral smoker’s lines, periorbital crow’s feet, and horizontal neck creases with seamless tissue integration and zero risk of the Tyndall effect.
Detailed Description
Celosome Soft is an advanced, sterile, non-pyrogenic physiological cross-linked sodium hyaluronate injectable developed by ExoCoBio (South Korea). Formulated with the lowest viscosity and softest elasticity in the Celosome portfolio, it is designed specifically for delicate dermal planes where higher-density fillers would risk palpable nodules or visible ridges.
Utilizing proprietary HENM technology, Celosome Soft arranges cross-linked hyaluronic acid into an ultra-fine, equalized 3D membrane network. The hydrogel undergoes an exhaustive 8-stage membrane dialysis process that removes residual unreacted BDDE to virtually undetectable levels, ensuring exceptional tissue biocompatibility and minimizing post-injection erythema or swelling. The resulting fluid gel spreads evenly into the superficial reticular and papillary dermis, restoring natural dermal hydration and mechanically effacing fine dynamic etchings without altering natural facial expressions.
Treatment Areas & Indications
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Periorbital & Perioral Delicate Lines:
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Superficial lateral canthal rhytids (Crow’s feet)
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Fine perioral vertical lines (Smoker’s lines / barcode lines)
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Subtle under-eye fine crepiness and superficial tear trough feathering
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Superficial Facial Rhytids:
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Shallow horizontal forehead creases
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Fine superficial glabellar frown lines
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Accordion smile lines and fine cheek crepiness
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Neck & Décolletage Rejuvenation:
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Horizontal neck rings (“Tech Neck” / necklace creases)
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Décolletage fine lines and sleep crepiness
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Key Clinical Advantages
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Patented HENM Fluid Rheology: Provides gentle cohesive elasticity that flows smoothly into shallow dermal valleys, eliminating surface irregularities, lumps, or over-correction.
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Zero Tyndall Discoloration: High purification and uniform light-refracting hydrogel properties ensure that superficial intradermal placement does not cause bluish skin discoloration.
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8-Stage Dialysis Purity: Multi-step membrane dialysis strips away chemical residues and endotoxins, promoting rapid recovery with negligible downtime, swelling, or redness.
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10% Volume Advantage (1.1 mL Syringe): Supplied in a 1.1 mL syringe format, delivering 10% extra product compared to the 1.0 mL industry standard for complete coverage of multi-zone fine lines.
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Integrated 0.3% Lidocaine: Infused with lidocaine hydrochloride to numb sensitive, highly innervated areas (like periorbital and perioral zones), maximizing patient procedural comfort.
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Effortless Micro-Extrusion: Glides effortlessly through ultra-fine 30G needles, providing high volumetric precision and minimizing injection trauma and bruising.
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Sustained Superficial Longevity: Maintains smooth, refined skin texture and line correction for 6 to 9 months.
Technical Specifications
| Parameter | Specification |
| Active Substance | Cross-linked Sodium Hyaluronate + 0.3% Lidocaine Hydrochloride |
| HA Concentration | 24 mg/mL |
| Lidocaine Concentration | 3 mg/mL (0.3% w/v) |
| Cross-Linking Technology | HENM (High concentration Equalized cross-linked Network Membrane) |
| Syringe Volume | 1 x 1.1 mL pre-filled sterile glass syringe |
| Included Needles | 2 x 30G 1/2” (13 mm) ultra-thin wall disposable needles |
| Target Injection Plane | Superficial-to-mid dermis |
| Recommended Injection Techniques | Serial micro-puncture, linear threading, blanching-style superficial pass, or micro-papular nappage |
| Expected Clinical Duration | 6 to 9 months (dependent on skin quality, depth, and patient metabolism) |
| Storage Instructions | Store between 2°C to 25°C (36°F to 77°F); protect from direct sunlight and freezing |
| Manufacturer | ExoCoBio Co., Ltd. |
| (South Korea) | Regulatory Category | Medical Device / CE-marked / Prescription Only (Rx) |
Professional Advisory: Celosome Soft with Lidocaine is a medical-grade injectable device intended strictly for certified dermatologists, plastic surgeons, and credentialed aesthetic physicians trained in superficial dermal injection and micro-puncture techniques. Not authorized for non-clinical consumer use.






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